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Steady-state peak plasma clarithromycin concentrations were attained within three days and were approximately 3 to 4 mcg/mL with a 500 mg dose administered every eight to 12 hours. Show On This Page, view All, rx only. A prospective study of 51 pediatric patients at a poison-control center suggested that overdosages of less than 250 mg/kg of amoxicillin are not associated with significant clinical symptoms and do not require gastric emptying.2 Interstitial nephritis resulting in oliguric renal failure has been reported. Saquinavir (in patients with decreased renal function) Saquinavir: When saquinavir is black and white car rental coupon coadministered with ritonavir, consideration should be given to the potential effects of ritonavir on clarithromycin (refer to ritonavir above). If you use our sites or applications on or after February 20th, 2018, you are agreeing to the new.